Table 2 Comparison of all collected data between neonates with and without sepsis (univariate analysis)
Variable | With sepsis | Without sepsis | P |
|---|---|---|---|
N = 514 (%) | N = 11276 (%) | ||
Neonate-related | |||
Gender (feminine/masculine) | 233/281 | 5542/5732 | 0.22 |
Gestational age (wk)* | 34 ± 4.3 | 39 ± 2.3 | <0.0001 |
Birth weight (g)* | 2069 ± 837 | 3053 ± 576 | <0.0001 |
Height (cm)* | 43.4 ± 5.9 | 49.3 ± 3.3 | <0.0001 |
Premature (≤37 wks) | 350 (68.1) | 1581 (14.0) | <0.0001 |
Postmature (≥42 wks) | 5 (1.0) | 131 (1.2) | 0.45 |
Product of multiple pregnancy | 41 (8.0) | 204 (1.8) | <0.0001 |
Abnormal umbilical cord | 131 (25.5) | 1620 (14.4) | <0.0001 |
With perinatal asphyxia | 17 (3.3) | 81 (0.7) | <0.0001 |
With intrauterine hypoxia | 10 (1.9) | 71 (0.6) | 0.003 |
Apgar score ≤5 | 274 (53.3) | 1,765 (15.7) | <0.0001 |
With fetal distress | 86 (16.7) | 896 (7.9) | <0.0001 |
Maternal-related | |||
Age (yrs)* | 26 ± 5.5 | 25 ± 5.4 | 0.10 |
Low educative level | 284 (55.3) | 6341 (56.2) | 0.341 |
Gestations* | 2 ± 1.2 | 2 ± 1.1 | 0.01 |
Deliveries* | 0.5 ± 0.9 | 0.6 ± 0.9 | 0.001 |
Non-adequate pregnancy control | 258 (50.2) | 4112 (36.5) | <0.0001 |
Experienced threat of abortion during this pregnancy | 139 (27.0) | 1905 (16.9) | <0.0001 |
Abnormal placenta | 86 (16.7) | 436 (3.9) | <0.0001 |
Dystocic delivery | 151 (24.9) | 5900 (52.3) | <0.0001 |
Cesarean section | 359 (69.8) | 5232 (46.4) | <0.0001 |
Abnormal amniotic fluid | 159 (30.9) | 1687 (15.0) | <0.0001 |
Premature membrane rapture > 12 h | 168 (32.7) | 469 (4.2) | <0.0001 |
Premature membrane rapture > 24 h | 137 (26.7) | 222 (2.0) | <0.0001 |
Premature membrane rapture > 48 h | 85 (26.7) | 105 (0.9) | <0.0001 |
Amnionitis | 4 (0.8) | 32 (0.3) | 0.074 |
Preeclampsia ≤35 gestational wks | 28 (5.4) | 340 (3.0) | <0.0001 |
Preeclampsia >35 gestational wks | 26 (5.1) | 569 (5.0) | 0.530 |
Metabolic disease ≤35 gestational wks | 27 (5.3) | 326 (2.9) | 0.002 |
Metabolic disease >35 gestational wks | 26 (5.1) | 343 (3.0) | 0.007 |
Infectious disease ≤35 gestational wks | 164 (31.9) | 2793 (24.8) | <0.0001 |
Infectious disease >35 gestational wks | 79 (15.4) | 1270 (11.3) | 0.003 |
Clinical-course and medical-care related | |||
Reanimation required | 339 (66.0) | 3888 (34.5) | <0.0001 |
Mechanical ventilation required | 160 (31.1) | 209 (1.9) | <0.0001 |
O2 inspiration fraction required > 60% | 95 (18.5) | 96 (0.9) | <0.0001 |
Continuous positive airway pressure required | 24 (4.7) | 14 (0.01) | <0.0001 |
Surfactant administration | 49 (9.5) | 34 (0.3) | <0.0001 |
Respiratory complication | 35 (6.8) | 91 (0.8) | <0.0001 |
Intraventricular bleeding | 20 (3.9) | 28 (0.2) | <0.0001 |
Surgical procedure required | 14 (2.7) | 10 (0.1) | <0.0001 |
Medical procedure required | 293 (57.0) | 609 (5.4) | <0.0001 |