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Table 1 Comparison of characteristics of mother-newborn pairs in full cohort versus subset with lymphocyte immunophenotype versus subgroup with Volatile Organic Compounds personal assessment and lymphocyte immunophenotype

From: Maternal exposure to air pollution before and during pregnancy related to changes in newborn's cord blood lymphocyte subpopulations. The EDEN study cohort

Factor Full cohort (n = 2002) Total study sample (n = 370) P-value (full cohort vs. total study sample) Non-smoking mothers with BETX assessment (n = 56) P-value (Total study sample vs. subset of 56)
Mother's age, mean ± SD, years 29.99 ± 4.89 29.77 ± 4.72 0.39 29.25 ± 3.64 0.37
19 - 24.9 (%) 11.71 9.88 0.26 3.7 0.12
25 - 34.9 (%) 70.95 74.55   87.04  
> 35 (%) 17.34 15.57   9.26  
BMI, mean ± SD, kg/m2 26.32 ± 4.46 25.89 ± 4.10 0.1 25.00 ± 3.37 0.13
Normal (%) 45.09 48.77 0.22 57.14 0.56
Overweight (%) 37.82 36.78   35.71  
Moderate obesity (%) 12.13 11.44   5.36  
Severe obesity (%) 3.69 1.91   1.79  
Morbid obesity (%) 1.27 1.09   0  
Employment status, % 71.23 74.12 0.17 78.57 0.48
Full-time 77.4 77.74 0.9 80 0.73
Part-time 22.6 22.26   20  
Passive smoking, %      
During 1st trimester 30.68 32.25 0.47 28.57 0.58
During 2nd trimester 28.62 28.73 0.96 25 0.56
During 3rd trimester 26.21 25.75 0.82 25 0.91
Active smoking , %      
Before pregnancy 36.28 32.97 0.1 23.21 0.14
During 1st trimester 25.84 20.71 0.01 0 0.04
During 2nd trimester 17.55 15.26 0.19 0 0.001
During 3rd trimester 16.73 17.12 0.82 0 0.002
Maternal history of allergies, % 51.74 51.1 0.78 51.79 0.92
Gestational duration, mean ± SD, weeks 39.22 ± 1.75 39.41 ± 1.22 0.54 39.45 ± 1.16 0.72
< 37 weeks (%) 6.17 2.43 0.004 1.79 0. 09
≥ 37 weeks (%) 93.83 97.57   98.21  
Birth weight, mean ± SD, g 3279 ± 585 3343 ± 456 0.05 3359 ± 396 0.58
< 2, 500 g (%) 10.61 2.43 < 0.0001 1.79 0.09
≥ 2, 500 g (%) 89.39 97.57   98.21  
Newborn's sex , %      
Male 52.55 49.19 0.15 57.14 0.27
Female 47.45 50.81   42.86  
Season of birth*, %      
Autumn 22.22 16.8 0.003 14.29 0.43
Winter 21.03 22.76   30.36  
Spring 30.17 36.59   39.29  
Summer 26.58 23.85   16.07  
  1. SD, standard deviation; BTEX = benzene, ethylbenzene, toluene, xylenes; * calendar defined.