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Table 3 Association between maternal systemic/localized comorbidity and preterm birth (PTB) by clinical subtype

From: Association between maternal comorbidity and preterm birth by severity and clinical subtype: retrospective cohort study

 

Unadjusted OR (95% CI)

Adjusted OR (95% CI)*

Population attributable fraction

All PTB

   

   Systemic comorbidity

1.67 (1.64-1.69)

1.66 (1.63-1.68)

12.8

   Localized comorbidity

2.23 (2.20-2.27)

2.27 (2.24-2.31)

16.9

Medically indicated PTB

   

   Systemic comorbidity

4.11 (4.00-4.22)

4.01 (3.90-4.11)

21.8

   Localized comorbidity

4.88 (4.76-5.01)

4.83 (4.71-4.96)

23.3

PPROM †

   

   Systemic comorbidity

1.23 (1.19-1.26)

1.18 (1.15-1.22)

8.0

   Localized comorbidity

1.85 (1.80-1.90)

1.83 (1.78-1.88)

21.1

Spontaneous PTB ‡

   

   Systemic comorbidity

0.99 (0.97-1.02)

1.00 (0.97-1.02)

0

   Localized comorbidity

1.31 (1.28-1.35)

1.38 (1.34-1.42)

5.8

  1. * Odds ratio (OR), 95% confidence interval (CI) adjusted for maternal age, grand multiparity, and period
  2. † Preterm premature rupture of membranes
  3. ‡ Spontaneous preterm labour before 37 weeks of gestation with intact membranes